News and events

Sustaining improvements in the management of infants with bronchiolitis – a PREDICT study

Co-ordinating PI

Emma Tavender/Sandy Middleton/Stuart Dalziel/ Ed Oakley

Study Co-ordinator

Emma Tavender/Tory Ramsden (PhD student)

Aim/s:

The aim of this study is to:

1. determine if the use of targeted interventions from the PREDICT Bronchiolitis KT Study have been effective at sustaining improvements in evidence-based practices in Australasian paediatric acute care settings one and two years after completion of the trial at intervention group hospitals (n=13);
2. determine if there are any improvements in control group hospitals (n=13);
3. understand the factors which influenced the sustainability of improvements in intervention group hospitals and;
4. explore factors which may have contributed to improvements at control group hospitals.

Study design:

A mixed-methods study design: retrospective medical record audit (approximately 150 infants per site for the years 2018 and 2019) and qualitative semi-structured individual or group interviews (3-5 individuals per site).

Primary outcomes:

• Outcomes: medical record audit:
  The proportion of infants presenting with bronchiolitis to intervention and control group hospitals, who received care that adhered with five inappropriate therapies (chest X-ray, salbutamol, glucocorticoids, antibiotics, and adrenaline) one year (2018) and two years (2019) following delivery of an intervention designed to promote evidence-based practice adherence (composite of all five practices).
• Outcomes: Qualitative interviews:
  Factors that contributed to sustainability of improvements of evidence-based practice adherence at intervention group hospitals four years post-implementation; Factors that contributed to improvements/deterioration of evidence-based practice adherence at control group hospitals four years post-implementation; Fidelity and adaptation to the PREDICT Bronchiolitis KT Study implementation strategy at intervention and control group hospitals four years following intervention delivery (2018, 2019, 2020, 2021) (Control group hospitals received the intervention materials post trial completion).

Current status:

• 16 Australian and 6 New Zealand sites recruited. All sites have completed governance and commenced the study. Medical Record Audit data collection has been completed at all 21 sites. Qualitative interviews are now completed at all 12 Australian and New Zealand intervention hospitals.
• Conducting preliminary data analysis.

Publication:

Ramsden, V., Babl, F.E., Dalziel, S.R. et al. Sustainability of evidence-based practices in the management of infants with bronchiolitis in hospital settings – a PREDICT study protocol. BMC Health Serv Res 22, 1099 (2022). https://doi.org/10.1186/s12913-022-08450-z.

 

Our “Getting to Know You” segment ensures PREDICT members are aware of new members, their interests and areas of expertise and where they are located.

This month we introduce Kate Loveys, Research Fellow from the University of Auckland.

“I am a Research Fellow at the Department of Paediatrics: Child and Youth Health at the University of Auckland School of Medicine in Auckland, New Zealand, where I work with Prof Stuart Dalziel and Dr Libby Haskell. I am also a Consultant for the World Health Organization (Department of Maternal, Newborn, Child and Adolescent Health and Ageing). In my Research Fellow role, I am supporting the development of PREDICT’s Australasian bronchiolitis guideline update through performing evidence syntheses and appraisals, and running a qualitative study with families of children who were hospitalised for bronchiolitis. My PhD is in Health Psychology and I have a background in evidence synthesis, guideline development, and digital health research involving quantitative and qualitative methodologies.”

Welcome to PREDICT Kate!

 

 

 

 

 

PREDICT has been awarded a $3.8 million Rapid Applied Research Translation (RART) grant to spearhead a nation-wide project to boost healthcare and research across regional and rural Australia – with a focus on bronchiolitis. Bronchiolitis is an acute lung disease caused by viral infections and the most common reason for hospital admissions in infants.

This study will bring together clinicians and researchers across craft groups and specialties from nursing, paediatrics, general practice, emergency, and intensive care to improve bronchiolitis care and build national capacity in research, implementation of research evidence and innovation.  Thirty different hospitals from rural, regional and urban areas will be involved.

Ultimately, the aim is to ensure that no matter where a young child is in Australia, they are able to receive the best possible care for acute illnesses.

 

 

 

Congratulations to the following PREDICT authors:

Long E, Borland ML, George S, Jani S, Tan E, Neutze J, Phillips N, Kochar A, Craig S, Lithgow A, Rao A, Dalziel S, Oakley E, Hearps S, Singh S, Gelbart B, McNab S, Balamuth F, Weiss S, Kuppermann N, Williams A, Babl FE; Paediatric Research In Emergency Departments International Collaborative (PREDICT); Children’s Inpatient Research Collaborative of Australia and New Zealand (CIRCAN). Sepsis epidemiology in Australian and New Zealand children (SENTINEL): protocol for a multicountry prospective observational study. BMJ Open. 2024 Jan 12;14(1):e077471. doi: 10.1136/bmjopen-2023-077471. PMID: 38216206.

Robertson T, Borland ML, O’Brien S, Haskell L, Babl FE, Dalziel SR, Tavender E. Understanding the uptake and adaption of targeted implementation interventions for reducing bronchiolitis investigations and therapies. Acta Paediatr. 2024 Jan 8. doi: 10.1111/apa.17090. Epub ahead of print. PMID: 38189212.

Craig S, Collings M, Gray C, Benito J, Velasco R, Lyttle MD, Roland D, Schuh S, Shihabuddin B, Kwok M, Mahajan P, Johnson M, Zorc J, Khanna K, Fernandes R, Yock-Corrales A, Santhanam I, Cheema B, Ong GY, Jaiganesh T, Powell C, Nixon G, Dalziel S, Babl FE, Graudins A. Analysis of guideline recommendations for treatment of asthma exacerbations in children: a Pediatric Emergency Research Networks (PERN) study. Arch Dis Child. 2024 Feb 7:archdischild-2023-326739. doi: 10.1136/archdischild-2023-326739. Epub ahead of print. PMID: 38325912.

Sasse R, Borland ML, George S, Jani S, Tan E, Neutze J, Phillips N, Kochar A, Craig S, Lithgow A, Rao A, Dalziel SR, Williams A, Babl FE, Went G, Long E; Paediatric Research in Emergency Departments International Collaborative (PREDICT) Network. Appraisal of Australian and New Zealand paediatric sepsis guidelines. Emerg Med Australas. 2024 Feb 25. doi: 10.1111/1742-6723.14381. Epub ahead of print. PMID: 38403429.

The first of our education sessions is scheduled for 7th March from 11am-12noon (AEDT), it will include: 

• Different types of research designs
• Consumer Involvement

Calendar invites have been forwarded.  See timetable for further details of sessions and topics for the remainder of the year.

A series of online research education sessions will be held bi-monthly throughout 2024.  All PREDICT members are invited to attend, however sessions will be recorded and uploaded to the PREDICT website if you want to tune in later.

The first session is scheduled for 7th March from 11am-12noon (AEDT) with calendar invites emailed shortly.  Topics to be covered in our inaugural session are different types of research designs and consumer involvement.  See timetable for further details.

Dates for the remaining sessions for 2024 are still to be confirmed with sessions running between one to two hours depending on the content. See timetable here.

 

 

 

Our “Getting to Know You” segment ensures PREDICT members are aware of new members, their interests and areas of expertise and where they are located.

This month we introduce Valerie Astle from Perth Children’s Hospital.

“I’m a FACEM PEM at Perth Children’s Hospital. I sit at the desk next to Prof Meredith Borland and so it is hard not to become enveloped in the world of research. I joined PREDICT out of interest in research and because I sit on the ACEM national PEM network and the WA PEM network committees and would like to be able to inform the members about the latest research paper results.”

Welcome to PREDICT Val!

 

 

 

 

 

Our “Getting to Know You” segment ensures PREDICT members are aware of new members, their interests and areas of expertise and where they are located.

This month we introduce Weihao Lee from Perth Children’s Hospital.

“I’m a paediatric Advanced Trainee currently working at Perth Children’s Hospital, the sole tertiary paediatric hospital in Western Australia. I am interested in paediatric emergency medicine and clinical research, and am one of the investigators on the Study of Paediatric Appendicitis Scores and Management Strategies (SPASMS) looking at clinical prediction scores in paediatric appendicitis for which I am currently undertaking a PhD at the University of Western Australia under the supervision of Professor Meredith Borland. I am also currently involved in research looking at child protection referrals and the use of injury proformas in ED in my role as the Child Protection Unit fellow.”

Welcome to PREDICT Weihao!

 

 

 

 

 

Current PREDICT members recently received an email with a link to the members database, where they will be asked to review and update their existing information. Details previously completed will appear in the form so you are only required to check the information and update if necessary. We are allowing 6 weeks to complete the form with the final date for completion being 29/02/24. The process takes approximately 2 minutes and we will send you a weekly reminder.

Once the form is submitted, your membership is automatically renewed and valid until February 2026.

If the form is not completed by the deadline, we will assume that you no longer wish to remain a member and will remove you from our contact list.

We ask that you respond promptly to ensure your membership data remains current.

Congratulations to the following PREDICT authors:

Craig S, Xu Y, Robas K, Iramain R, Yock-Corrales A, Soto-Martinez ME, Rino P, Belen Alvarez Ricciardi M, Piantanida S, Mahant S, Ubuane PO, Odusote O, Kwok M, Johnson MD, Paniagua N, Benito Fernandez J, Ong GY, Lyttle MD, Gong J, Roland D, Dalziel SR, Nixon GM, Powell CVE, Graudins A, Babl FE; Pediatric Emergency Research Networks (PERN). Core outcomes and factors influencing the experience of care for children with severe acute exacerbations of asthma: a qualitative study. BMJ Open Respir Res. 2023 Nov;10(1):e001723. doi: 10.1136/bmjresp-2023-001723. PMID: 37968074; PMCID: PMC10661079.

Babl FE, Eapen N, Herd D, Borland ML, Kochar A, Lawton B, Hort J, West A, George S, Davidson A, Cheek JA, Oakley E, Hopper SM, Berkowitz RG, Wilson CL, Williams A, MacKay MT, Lee KJ, Hearps S, Dalziel SR. Pain in children with Bell’s palsy: secondary analysis of a randomised controlled trial. Archives of Disease in Childhood. Published Online First: 02 December 2023. doi: 10.1136/archdischild-2023-325381

Babl FE, Herd D, Borland ML, Kochar A, Lawton B, Hort J, West A, George S, Oakley E, Wilson CL, Hopper SM, Cheek JA, Hearps S, Mackay MT, Dalziel SR, Lee KJ. Facial Function in Bell’s Palsy in a Cohort of Children Randomized to Prednisolone or Placebo 12 months after Diagnosis. Pediatric Neurology. Published online 2024 Jan 11. ISSN 0887-8994, https://doi.org/10.1016/j.pediatrneurol.2024.01.011.

Crowe LM, Rausa VC, Anderson V, Borland ML, Kochar A, Lyttle MD, Gilhotra Y, Dalziel SR, Oakley E, Furyk J, Neutze J, Bressan S, Davis GA, Babl FE; Paediatric Research in Emergency Departments International Collaborative (PREDICT). Mild Traumatic Brain Injury Characteristics and Symptoms in Preschool Children: How Do They Differ to School Age Children? A Multicenter Prospective Observational Study. Arch Phys Med Rehabil. 2024 Jan;105(1):120-124. doi: 10.1016/j.apmr.2023.08.008. Epub 2023 Sep 14. PMID: 37715760.