2023
Babl FE, Eapen N, Herd D, Borland ML, Kochar A, Lawton B, Hort J, West A, George S, Davidson A, Cheek JA, Oakley E, Hopper SM, Berkowitz RG, Wilson CL, Williams A, MacKay MT, Lee KJ, Hearps S, Dalziel SR. Pain in children with Bell’s palsy: secondary analysis of a randomised controlled trial. Archives of Disease in Childhood. Published Online First: 02 December 2023. doi: 10.1136/archdischild-2023-325381 [Link]
Craig S, Xu Y, Robas K, Iramain R, Yock-Corrales A, Soto-Martinez ME, Rino P, Belen Alvarez Ricciardi M, Piantanida S, Mahant S, Ubuane PO, Odusote O, Kwok M, Johnson MD, Paniagua N, Benito Fernandez J, Ong GY, Lyttle MD, Gong J, Roland D, Dalziel SR, Nixon GM, Powell CVE, Graudins A, Babl FE; Pediatric Emergency Research Networks (PERN). Core outcomes and factors influencing the experience of care for children with severe acute exacerbations of asthma: a qualitative study. BMJ Open Respir Res. 2023 Nov;10(1):e001723. doi: 10.1136/bmjresp-2023-001723. PMID: 37968074; [Link]
Curran J, Wozney L, Tavender E, Wilson C, Ritchie KC, Wong H, Gallant A, Somerville M, Archambault PM, Cassidy C, Jabbour M, Mackay R, Plint AC
Implementing Electronic Discharge Communication Tools in Pediatric Emergency Departments: Multicountry, Cross-Sectional Readiness Survey of Nurses and Physicians. JMIR Hum Factors 2023;10:e46379 doi: 10.2196/46379 PMID: 37819696 [Link]
Bourke EM, Douglas N, Wilson CL, Anderson D, Nehme Z, Babl FE; Paediatric Research in Emergency Departments International Collaborative (PREDICT). Acute Severe Behavioral Disturbance Requiring Parenteral Sedation in Pediatric Mental Health Presentations to Emergency Medical Services: A Retrospective Chart Review. Ann Emerg Med. 2023 Nov;82(5):546-557. doi: 10.1016/j.annemergmed.2023.04.028. Epub 2023 Jun 30. PMID: 37389492. [Link]
Parr M, Wilson CL, Jones B, Crawford NW, Ferguson S, Ramesh S, Eapen N, Craig S, Hearps S, Babl FE; Paediatric Research in Emergency Departments International Collaborative (PREDICT) Research Network. Emergency department presentations for chest complaints after mRNA COVID-19 vaccinations in children and adolescents. Emerg Med Australas. 2023 Oct 23. doi: 10.1111/1742-6723.14327. Epub ahead of print. PMID: 37872323. [Link].
Solan T, Cudini D, Humar M, Forsyth N, Meadley B, St Clair T, Hodge D, Smith K, Babl FE, Long E. Characteristics of paediatric pre-hospital intubation by Intensive Care Paramedics. Emerg Med Australas. 2023 Oct;35(5):754-758. doi: 10.1111/1742-6723.14207. Epub 2023 Apr 5. PMID: 37019689. [Link].
Craig S, Delardes B, Nehme Z, Wilson C, Dalziel S, Nixon GM, Powell C, Graudins A, Babl FE; PREDICT Network. Acute paediatric asthma treatment in the prehospital setting: a retrospective observational study. BMJ Open. 2023 Jun 22;13(6):e073029. doi: 10.1136/bmjopen-2023-073029. PMID: 37349099; [Link]
Borland ML, O’Brien S, Tavender E, Haskell L, Babl FE, Schembri R, Smedley B, Mitenko H, Robertson T, Mukherjee A, Dalziel SR. Evaluation of targeted implementation interventions for reducing investigations and therapies in infants with bronchiolitis. Acta Paediatr. 2023 Aug;112(8):1747-1754. doi: 10.1111/apa.16786. Epub 2023 Apr 18. PMID: 37026175. [Link]
Ibrahim L, Wilson C, Tham D, Corden M, Jani S, Zhang M, Kochar A, Tan KF, George S, Phillips NT, Buntine P, Robins-Browne K, Chong V, Georgeson T, Lithgow A, Davidson S, O’Brien S, Tran V, Babl FE. The characteristics of SARS-CoV-2-positive children in Australian hospitals: a PREDICT network study. Med J Aust. 2023 Jun 5;218(10):460-466. doi: 10.5694/mja2.51934. Epub 2023 Apr 22. PMID: 37087105. [Link]
Xiong X, Huang L, Herd DW, Borland ML, Davidson A, Hearps S, Mackay MT, Lee KJ, Dalziel SR, Dalziel K, Cheek JA, Babl FE. Cost-effectiveness of Prednisolone to Treat Bell Palsy in Children: An Economic Evaluation Alongside a Randomized Controlled Trial. Neurology. 2023 Jun 13;100(24):e2432-e2441. doi: 10.1212/WNL.0000000000207284. Epub 2023 Apr 18. PMID: 37072220. [Link]
Franklin D, Babl FE, Neutze J, Craig S, Oakley E, Furyk J, Frampton CM, Hasan N, Pham TM, Miller L, Fraser JF, Dalziel SR, Schibler A; A Pediatric Acute Respiratory Intervention Study (PARIS) on behalf of PREDICT. Predictors of Intensive Care Admission in Hypoxemic Bronchiolitis Infants, Secondary Analysis of a Randomized Trial. J Pediatr. 2023 May;256:92-97.e1. doi: 10.1016/j.jpeds.2022.12.006. Epub 2022 Dec 14. PMID: 36528052. [Link]
Borland ML, Dalziel SR, Phillips N, Dalton S, Lyttle MD, Bressan S, Oakley E, Kochar A, Furyk J, Cheek JA, Neutze J, Eapen N, Hearps SJ, Rausa VC, Babl FE; Paediatric Research in Emergency Departments International Collaborative (PREDICT) group. Incidence of traumatic brain injuries in head-injured children with seizures. Emerg Med Australas. 2023 Apr;35(2):289-296. doi: 10.1111/1742-6723.14112. Epub 2022 Nov 2. PMID: 36323396. [Link].
George S, Gibbons K, Williams T, Humphreys S, Gelbart B, Le Marsney R, Craig S, Tingay D, Chavan A, Schibler A; Kids THRIVE Investigators; Paediatric Research in Emergency Departments International Collaborative (PREDICT); Australia, New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG). Transnasal Humidified Rapid Insufflation Ventilatory Exchange in children requiring emergent intubation (Kids THRIVE): a statistical analysis plan for a randomised controlled trial. Trials. 2023 May 31;24(1):369. doi: 10.1186/s13063-023-07330-z. PMID: 37259146; [Link]
Bourke EM, Knott JC, Craig S, Babl FE; Paediatric Research in Emergency Departments International Collaborative (PREDICT) Research Network. Management of paediatric acute severe behavioural disturbance in emergency departments across Australia: A PREDICT survey of senior medical staff. Emerg Med Australas. 2023 Apr;35(2):254-260. doi: 10.1111/1742-6723.14105. Epub 2022 Nov 3. PMID: 36328402. [Link]
Babl FE, Eapen N, Herd D, Borland ML, Kochar A, Zhang M, Oakley E, Hopper SM, Berkowitz RG, Wilson CL, Williams A, Mackay MT, Lee KJ, Hearps S; PREDICT (Paediatric Research in Emergency Departments International Collaborative) research network. Agreement of Clinician-Administered and Modified Parent-Administered House-Brackmann Scales in Children with Bell’s Palsy. OTO Open. 2023 Mar 24;7(1):e44. doi: 10.1002/oto2.44. PMID: 36998545; [Link]
Bourke EM, Borland ML, Kochar A, George S, Shellshear D, Jani S, Perkins K, Tham D, Gordon MS, Klein K, Prakash C, Lee K, Davidson A, Knott JC, Craig S, Babl FE; Paediatric research in Emergency Departments International Collaborative (PREDICT). Pharmacological Emergency management of Agitation in Children and Young people: protocol for a randomised controlled trial of intraMuscular medication (PEAChY-M). BMJ Open. 2023 Mar 30;13(3):e067436. doi: 10.1136/bmjopen-2022-067436. PMID: 36997241. [Link]
Bourke EM, Borland ML, Kochar A, George S, Shellshear D, Jani S, Perkins K, Tham D, Gordon MS, Klein K, Prakash C, Lee K, Davidson A, Knott JC, Craig S, Babl FE; Paediatric research in Emergency Departments International Collaborative (PREDICT). Pharmacological emergency management of agitation in children and young people: protocol for a randomised controlled trial of oral medication (PEAChY-O). BMJ Open. 2023 Mar 30;13(3):e067433. doi: 10.1136/bmjopen-2022-067433. PMID: 36997250. [Link]
O’Brien SL, Haskell L, Tavender EJ, Wilson S, Borland ML, Oakley E, Dalziel SR, Gill FJ. Factors influencing health professionals’ use of high-flow nasal cannula therapy for infants with bronchiolitis – A qualitative study. Front Pediatr. 2023 Mar 16;11:1098577. doi: 10.3389/fped.2023.1098577. PMID: 37009298. [Link]
Gray CS, Xu Y, Babl FE, Dalziel S, Powell CVE, Chong SL, Roland D, Lyttle MD, Fernandes RM, Benito J, Johnson M, Yock-Corrales A, Santhanam I, Schuh S, Cheema B, Couper J, Craig S; Pediatric Emergency Research Network (PERN). International perspective on research priorities and outcome measures of importance in the care of children with acute exacerbations of asthma: a qualitative interview study. BMJ Open Respir Res. 2023 Feb;10(1):e001502. doi: 10.1136/bmjresp-2022-001502. PMID: 36849194; PMCID: PMC9972434. [Link].
Williams A, Eapen N, Kochar A, Lawton B, Hort J, West A, George S, Berkowitz R, Lee KJ, Dalziel SR, Hearps S, Babl FE; PREDICT (Paediatric Research in Emergency Departments International Collaborative) research network. Agreement Between House-Brackmann and Sunnybrook Facial Nerve Grading Systems in Bell’s Palsy in Children: Secondary Analysis of a Randomized, Placebo-Controlled Multicenter Trial. J Child Neurol. 2023 Feb;38(1-2):44-51. doi: 10.1177/08830738221144082. Epub 2023 Feb 5. PMID: 36740927. [Link]
Franklin D, Babl FE, George S, Oakley E, Borland ML, Neutze J, Acworth J, Craig S, Jones M, Gannon B, Shellshear D, McCay H, Wallace A, Hoeppner T, Wildman M, Mattes J, Pham TMT, Miller L, Williams A, O’Brien S, Lawrence S, Bonisch M, Gibbons K, Moloney S, Waugh J, Hobbins S, Grew S, Fahy R, Dalziel SR, Schibler A. Effect of Early High-Flow Nasal Oxygen vs Standard Oxygen Therapy on Length of Hospital Stay in Hospitalized Children With Acute Hypoxemic Respiratory Failure: The PARIS-2 Randomized Clinical Trial. JAMA. 2023 Jan 17;329(3):224-234. doi: 10.1001/jama.2022.21805. PMID: 36648469 Clinical Trial. [Link]
2023 Presentations (conference proceedings, posters, published abstracts)
Sharon L. O’Brien, Libby Haskell, Emma J. Tavender, Sally Wilson, Meredith L. Borland, Ed Oakley, Stuart R. Dalziel, Rachel Schembri, and Fenella J. Gill. Poster presentation: Evidence based management of infants with bronchiolitis – why is it so hard? International Congress on Innovations and Leadership in Nursing and Midwifery (ICILNM) was held at The Westin Perth, Western Australia from 11 – 12 May 2023. [Poster presentation].More information
Aim: To determine a) prevalence of use and b) explore perceived factors influencing use of high flow nasal cannula (HFNC) therapy for infants with bronchiolitis within emergency departments and paediatric wards in Australia and New Zealand.
Method: Management and outcomes data were collected retrospectively for infants presenting with bronchiolitis to 26 hospitals between 1/5/2014 and 30/11/2017. Semi-structured interviews with nurses (7) and doctors (12) working in emergency and paediatric wards from four purposively selected hospitals. Deductive content analysis was used to map key influencing factors for use of HFNC therapy to the Theoretical Domains Framework.
Results: Of 11,715 infants, 3,392 (29.0%, 95% CI [28.1%, 29.8%]) received oxygen therapy; of whom 1,817 (53.6%, 95% CI [51.9%, 55.3%]) received HFNC. Use of oxygen therapy did not change over four years (p=0.12), while the proportion receiving HFNC increased (2014, 336/2,587 [43.2%]; 2017, 609/3,720 [57.8%]; p=<0.001). Increases in hospital LOS (p<0.001) and ICU admissions (p<0.001) were associated with HFNC use.
Influencing factors for HFNC use were mapped to the Theoretical Domains Framework with 21 themes identified. Key factors included clinicians’ expectations of mechanisms of HFNC to prevent patient deterioration, improve work of breathing and oxygen levels, staff emotions and social and environmental influences. These factors, combined with readily available equipment contributed to initiation of HFNC therapy.
Conclusion: HFNC therapy use increased over four years. Of infants who received oxygen therapy, the majority received HFNC therapy without improvement in hospital LOS or ICU admissions. Individual/personal and contextual/environmental factors contributed to the increased use.