PREDICT has been successful in securing RCH Foundation funding of $666,000.00 over 3 years for development of the Paediatric Adaptive Sepsis Platform Trial (PASSPORT) study.

A/Prof Elliot Long will lead the study which will use novel trial design to test multiple treatments for sepsis simultaneously with the aim of improving sepsis outcomes for children. The trial will incorporate adaptive enrolment, treatment allocation, and domain completion/commencement over time so that participants are always exposed to the best treatment combination.

Study planning and statistical simulations will commence mid-2024, with the aim to begin enrolment in 2026.