Sustaining improvements in the management of infants with bronchiolitis – a PREDICT study

The PREDICT ‘Knowledge Translation in Australasian Paediatric Acute Care’ (PREDICT KT study) (HREC/16/RC), a multicentred, cluster, randomised control trial of infants with Bronchiolitis demonstrated that use of targeted, theory-informed interventions (clinical leads, stakeholder meeting, train-the-trainer workshop, targeted educational package, audit/feedback) significantly improved compliance with five key non-evidence-based practice recommendations for bronchiolitis (chest x-ray, salbutamol, glucocorticoids, antibiotics, and adrenaline) in acute care settings by 14.1% (adjusted risk difference, 95% CI, 6.5%-21.7%; P < .001).

The aim of this study is to assess sustainability of improvements in reducing inappropriate therapies in infants with Bronchiolitis, at the 26 sites which participated in the PREDICT KT Study, one (2018) and two year (2019) post implementation of intervention. A retrospective medical audit and qualitative semi-structured interviews will be conducted at each site over two years following initial implementation of the KT Study interventions. Our results will help determine the sustainability of this intervention over time, determine any improvements in control group hospitals, examine the learning and decay effects of the intervention, determine fidelity and adaptation of the intervention and explore factors which may have contributed to sustained improvements in either intervention or control group sites.

Study design

Mixed Methods – Quantitative Retrospective Medical Record Audit and Qualitative Semi-structured interviews. 

Chief Investigators

A/Prof Emma Tavender
Professor Sandy Middleton

Timeframe

2022 – 2025

Funding

National Health and Medical Research Council ­ Centre for Research Excellence Grant ID 1171228.

Site locations

TBC

Sample

800 infants for 2018 and 1800 infants for 2019

Contact

emma.tavender@mcri.edu.au

Trial registration

ANZCTR (number: ACTRN12621001287820)