Author: MCRI

ED Clinicians – help us find parents for study reference group

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The Bronchiolitis season is upon us! 

Doctors and Nurses in regional and rural areas, can you help us to find parents of infants who have been treated for bronchiolitis in the ED?

What for? A Parent Advisory Group

In relation to what? The Regional and Rural Translation Bronchiolitis Study, (RART-Bronch). This MRFF funded research is based at the Murdoch Children’s Research Institute, at Royal Children’s Hospital Melbourne and endorsed by PREDICT. https://www.predict.org.au/projects/rart-bronch/

What’s it about?
This study aims to improve the hospital care of babies (<12 months) with bronchiolitis, in regional and rural hospitals.  It will do this by supporting doctors, nurses to give the right care and providing relevant information for families.  This research will involve nearly 30-40 hospitals across all states of Australia.

What’s the parent criteria?

  • Parent/ Carer resides in regional or rural Australia
  • Has presented to ED (locally) with an infant <12 months for bronchiolitis
  • Presented to ED in the past 18 months

What will they be asked to do?

  • Provide advice to the research team on topics relevant to families
  • Help us produce useful information for families about bronchiolitis
  • Help us communicate our research and study findings to families
  • All meetings will be online and they will be paid $50 per hour.

Found someone – what to do…..

If you find someone who meets the above criteria and think they may be interested, download this flyer here, ask them to email or text Cate Wilson – Project Manager. Cate will provide further information and follow up directly with the parent. 

Don’t hesitate to email or call if you have questions too. 

E: Catherine.wilson@mcri.edu.au

Thanks for our help!

Research education sessions

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The first of our education sessions is scheduled for 7th March from 11am-12noon (AEDT), it will include: 

  • Different types of research designs
  • Consumer Involvement

Calendar invites have been forwarded.  See timetable for further details of sessions and topics for the remainder of the year.

PREDICT Members Meeting – 15th November 2023 REGISTRATION NOW OPEN

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Registration is now open for the PREDICT members meeting to be held in November 2023.  This is a hybrid event so both face to face and virtual attendance is offered, however we are hoping for as many members as possible to attend in person. Registration via Trybooking is required for both modes of attendance.   See draft agenda.

PLEASE NOTE:  Registration closes on FRIDAY 27/10/23 and date cannot be extended.

DATE: Wednesday 15/11/23 (one day meeting)

TIME: 9.30am – 4.30pm

VENUE: The Cox Walford Room, Level 5 West, Murdoch Children’s Research Institute, 50 Flemington Rd, Parkville, Melbourne.

REGISTRATION

  • All attendees (virtual and face to face) must register via Trybooking and be a PREDICT member. Registration closes FRIDAY 27/10/23.
  • Please ensure you indicate dietary requirements during the booking process, regardless of whether or not you are attending the dinner, as catering will also be provided during the meeting.
  • If you wish to attend and are not a PREDICT member contact predict.mcri.edu.au regarding membership application prior to proceeding with Trybooking.
  • PREDICT will not sponsor attendance this year.  All accommodation and travel to be booked by the individual (excluding PREDICT executive members who will be attending the PREDICT executive meeting the day before).
  • Suggested accommodation close to RCH/MCRI
    The Larwill Art Series Hotel
    Mercure North Melbourne

    Dinner
  • The PREDICT dinner will be held on 14/11/2023 (NIGHT PRIOR TO MEETING) from 6.30pm – 9.00pm at the Leveson Hotel, 46 Leveson St, North Melbourne which is a short walk from the Larwill Hotel/MCRI.
  • The dinner includes a 3 course menu with a range of meat, seafood and vegetarian options.  Drinks are available at bar prices.
  • Payment of $60 (plus 50 cent booking fee) must be made via Trybooking during the registration process.  Choose “In person + dinner option”.
  • Booking and payment must be received by Friday 27/10/23.

QUESTIONS?

Please contact predict.mcri.edu.au.

Project Snapshot – BIPED

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BI-PED Study

A Randomised Controlled Trial Comparing Epinephrine and Dexamethasone to Placebo in the Treatment of Infants with Bronchiolitis

Co-ordinating PI:

Amy Plint (Canada), Ed Oakley (Australia), Stuart Dalziel (New Zealand)

Study Co-ordinator ANZ

Sharon O’Brien

Study design:

International, multicentre, Phase 111, double-blind, randomised controlled trial

For further details about the study please see: https://www.predict.org.au/new-projects/bi-ped-study/

Current status:

The research team are pleased to announce that the 5th season of the BIPED trial has been the most successful yet, reaching 598/864 participants recruited! The yearly recruitment was 28% of our total sample size; almost 100 more participants were enrolled in season 5 than were enrolled in season 4.

We have just over 30% (266) of our sample size left to recruit!
Please see below a number of charts which show study progress both locally and internationally.

CountrySiteTotal RecruitmentSeason 5 recruiment
CanadaChildren's Hospital of Eastern Ontario (CHE)
14236
CanadaCHU Sainte Justine (STJ)4712
CanadaAlberta Children's Hospital (ACH)449
CanadaStollery Children's Hospital (SCH)217
CanadaChildren's Hospital of Winnepeg (WPG)183
CanadaLondon Health Sciences (LHC)111
AustraliaPerth Children's Hospital (PCH)14360
AustraliaWomen's and Children's Hospital (WCH)4831
AustraliaMonash Medical Center (MMC)3626
New ZealandStarship Children's Hospital (SSH)5233
New ZealandKidz First Middlemore Hospital (KFH)2117
New ZealandWaikato Hospital) (WHH)155
TOTAL598239

New PREDICT publications

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Congratulations to the following PREDICT authors:

Parr M, Wilson CL, Jones B, Crawford NW, Ferguson S, Ramesh S, Eapen N, Craig S, Hearps S, Babl FE.
“Emergency Department Presentations for Chest Complaints after Mrna Covid-19 Vaccinations in Children and Adolescents.” Emerg Med Australas  (Accepted Sept. 2023, in press).

PhD Opportunity – UTAS – IMPACT project

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An exciting PhD opportunity to join the MRFF-funded Implementing clinical Pathways for Acute Care in Tasmania (IMPACT) project team, led by Dr Viet Tran (Royal Hobart Hospital and Statewide Director of Emergency Medicine Research).

The aims of the PhD are to improve care in Tasmanian EDs by embedding implementation science principles in health care systems and developing strategies to increase uptake of acute clinical pathways and reduce variations in care. The target acute care clinical improvement area will be co-developed with the candidate, dependent on clinical research interest.

Further details can be found here: Implementation Science improving ED care | University of Tasmania (utas.edu.au)) or contact Emma Tavender (emma.tavender@mcri.edu.au) if you have any specific questions.

Amit Kochar wins Research Award!

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Congratulations to Dr Amit Kochar who was awarded the Research and Innovation Award at the Women’s and Children’s Health Network Excellence Awards ceremony held on Friday, August 11th, 2023.

Amit has been a strong leader, motivating the team at WCHN to continuously strive for improvement and reach goals. Undoubtedly, achieving success in  research trials within the Paediatric Emergency Department is a collaborative effort involving a vast array of hospital personnel, nursing and medical staff.

Congratulations to Amit and the WCH team from PREDICT! 

 

 

Project Snapshot – PEACHY O & M

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PEAChY – O: Pharmacological Emergency management of Agitation in Children and Young people – A randomised controlled trial of Oral medication

Co-ordinating PI:  Elyssia Bourke

Study Co-ordinator: Kate Klein
Study design:

Randomised, controlled, open-label, multi-centre, phase III superiority effectiveness trial of: ORAL olanzapine vs ORAL diazepam.

For further background information see: https://www.predict.org.au/projects/peachy-o-and-peachy-m-studies/

Current status:

  • Study target sample size of 348 participants currently at 94% (N = 325 recruited). Nearing completion, over 12 months ahead of schedule!
  • PEAChY-O is on track to be complete by mid-September 2023.
  • Data cleaning is set to be finalised at all participating sites by late October, ready for final analysis.
  • An abstract is planned for presentation at the PAS in January 2024.

 

PEAChY- M: Pharmacological Emergency management of Agitation in Children and Young people – A randomised controlled trial of IntraMuscular medication

Study design:

Randomised, controlled, open-label, multi-centre, phase III superiority effectiveness trial of: INTRAMUSCULAR olanzapine vs INTRAMUSCULAR droperidol.

For further background information see: https://www.predict.org.au/projects/peachy-o-and-peachy-m-studies/

Current status:

  • Currently, 36% of the total number of participants required to meet the target sample size of 348 have been recruited.
  • Low recruitment across all sites due to several reasons. For example, management of ASBD events in the ED environment can be challenging and, commonly, many enrolled participants subsequently de-escalate (in behaviour) and no longer require IM medication (i.e. they either accept oral medication or no longer require any medication).
  • Education of clinical staff related to PEAChY-M continues at all sites to improve recruitment rates.

SAVE THE DATE – PREDICT members meeting 15th November 2023

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The PREDICT members meeting has been moved to 15th November 2023.  An amended calendar invite has been forwarded to all members.  Please accept the invite to ensure you have the correct date in your calendar.

The event will be held in Melbourne at the Murdoch Children’s Research Institute.
Registrations for the meeting via Try Booking will open in late September – you will be notified of this.

Present your “New Research Idea” at PREDICT Members meeting (15/11/23)

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We have scheduled up to three  “New research idea” presentations at the PREDICT members meeting being held face to face and via ZOOM on Wednesday 15th of November 2023.

Do you have a proposal you would like to develop and present for feedback?

If so, please email the PREDICT research co-ordinator Catherine.wilson@mcri.edu.au, a 1 – 2 page proposal by Friday 15th September 2023.

The 3 researchers selected to present their idea will receive mentoring from one of the PREDICT Executive with relevant expertise.

Presenters will be given 5 minutes to present the idea with an extra 10 minutes for discussion and questions. Presentations will be confirmed by 13th October 2023 and presentation times given later on.

 

We look forward to hearing from you soon!