PREDICT Bronchiolitis

CRIB2

Admitted patients with bronchiolitis at 7 Australian and New Zealand Centres: Retrospective analysis of epidemiological data

The CRIB2 study is a retrospective chart review of all the patients who were identified during the Comparative Rehydration in Bronchiolitis (CRIB) study, a randomised controlled trial that was completed in 2011. 3919 patients were admitted with bronchiolitis from 2009 – 2011 and assessed for eligibility as part of the CRIB study. These patients’ records will be analysed to look at the overall epidemiology of admitted patients with bronchiolitis; outcomes in patients with pre-existing medical conditions admitted with bronchiolitis; seasonal and geographical variation of admission characteristics and nasopharyngeal aspirates (NPA); intensive care interventions; and the use of inhaled bronchodilators and oral steroids in admitted patients with bronchiolitis.

Study design

Multi-centre retrospective audit of medical records

Completed

Infection/ Sepsis

Ed Oakley

Time frame

2012 – 2014

Funding

N/A


  • Royal Children’s Hospital, Melbourne, Australia
  • Princess Margaret Hospital, Perth, Australia
  • Sunshine Hospital, St Albans, Melbourne, Australia
  • Kidzfirst, Middlemore Hospital, Auckland, New Zealand
  • Monash Children’s Hospital, Melbourne, Australia
  • Royal Children’s Hospital, Brisbane, Australia
  • Starship Children’s Hospital, Auckland, New Zealand

Sample

3919 patients (aged 2 – 12 months) admitted with bronchiolitis who were assessed for eligibility as part of the CRIB study

Contact

ed.oakley@rch.org.au

Publications to date

Oakley E., Carter R., Murphy B., Borland M., Neutze J., Acworth J., Krieser D., Dalziel S., Davidson A., Donath S., Jachno K., South M., Babl FE., (PREDICT). Economic evaluation of nasogastric versus intravenous hydration in infants with bronchiolitis. Emerg Med Australas. 2016 Dec 22. doi: 10.1111/1742-6723.12713. PMID: 28004493 link.

Oakley E., Bata S., Rengasamy S., Krieser D., Cheek J., Jachno K., Babl FE. Nasogastric Hydration in Infants with Bronchiolitis Less Than 2 Months of Age. J Pediatr. 2016 Nov;178:241-245.e1. doi: 10.1016/j.jpeds.2016.07.012. Link

Paediatric Research in Emergency Departments International Collaborative, Oakley E., Babl F. E., Acworth J., Borland M., Kreiser D., Neutze J., Theophilos T., Donath S., South M., and Davidson A., ‘A Prospective Randomised Trial Comparing Nasogastric with Intravenous Hydration in Children with Bronchiolitis (Protocol): The Comparative Rehydration in Bronchiolitis Study (Crib)’, BMC Pediatr, (2010) 10, 37. link