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Evidence-based approach to the use of respiratory support

Figure 1. Evidence-based approach to the use of respiratory support in infants with bronchiolitis.

FiO2 = fractional concentration of inspired oxygen; HF = Humidified high flow; nCPAP = nasal continuous positive airway pressure.
1For otherwise healthy infants aged ≥6 weeks: SpO2 persistently <90%. For infants aged <6 weeks, or infants <12 months with an underlying health condition: SpO2 persistently <92%.
2Response to therapy (low-flow or HF oxygen therapy) is determined by a reduction in respiratory rate, a reduction in heart rate, or a paediatric early warning score within 4-5 hours of commencing therapy.
3If at any time, the infant has severe respiratory distress, escalate care. Respiratory distress is a subjective finding. Severe respiratory distress is a level where a senior clinician determines that escalation in care is required, transferring the patient to the emergency department resuscitation area, paediatric ward resuscitation area, high dependency unit, or intensive care unit. Junior staff should escalate concerns regarding severe respiratory distress to senior colleagues.