Project Snapshot – Sustaining improvements in the management of infants with bronchiolitis – a PREDICT study

The PREDICT ‘Knowledge Translation in Australasian Paediatric Acute Care’ (PREDICT KT study) (HREC/16/RC), a multicentred, cluster, randomised control trial of infants with Bronchiolitis, demonstrated that use of targeted, theory-informed interventions (clinical leads, stakeholder meeting, train-the-trainer workshop, targeted educational package, audit/feedback) significantly improved compliance with five key non-evidence-based practice recommendations for bronchiolitis (chest x-ray, salbutamol, glucocorticoids, antibiotics, and adrenaline) in acute care settings by 14.1% (adjusted risk difference, 95% CI, 6.5%-21.7%; P < .001).

The aim of this study is to assess sustainability of improvements in reducing inappropriate therapies in infants with Bronchiolitis, at the 26 sites which participated in the PREDICT KT Study, one (2018) and two year (2019) post implementation of intervention. A retrospective medical audit and qualitative semi-structured interviews will be conducted at each site over two years following initial implementation of the KT Study interventions. Our results will help determine the sustainability of this intervention over time, determine any improvements in control group hospitals, examine the learning and decay effects of the intervention, determine fidelity and adaptation of the intervention and explore factors which may have contributed to sustained improvements in either intervention or control group sites.

Link to further project details

  • Ethics approval has been received for Australian sites and provisional ethics approval has been received for New Zealand sites.
  • Sites will only be recruited if they participated in the PREDICT KT Study. Currently, 16 of the 20 Australian sites have agreed to participate.
  • Governance approvals are underway for the 16 Australian sites, with hopes to commence recruitment at these within the first half of 2022.
  • A protocol manuscript has been drafted and will be submitted for publication soon.